Cetirizine Dihydrochloride Syrup

Therapeutic Indication

Allergic rhinitis

Sneezing and runny nose

Itching and watery eyes

Skin allergies and urticaria

Dust and seasonal allergies

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Cetirizine Dihydrochloride

Syrup

Cetirizine Syrup is an antihistamine formulation used for the relief of allergic conditions such as sneezing, runny nose, watery eyes, itching, and skin allergies. It helps block the action of histamine, a substance responsible for allergic reactions in the body.
The formulation provides effective relief from seasonal and perennial allergic symptoms while causing minimal sedation compared to first-generation antihistamines. It is commonly used in both pediatric and adult patients for allergy management.

Speciality	Allergy Care \| General Medicine
Tags	Antihistamine \| Allergy Relief \| Anti-Allergic \| Pediatric Care
Strength	Cetirizine Dihydrochloride – 5 mg / 5 ml
Packing Size	30 ml Bottle 60 ml Bottle

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Mechanism

Cetirizine works by selectively blocking peripheral histamine H1 receptors, thereby reducing allergic symptoms such as itching, swelling, sneezing, and nasal discharge.

Benefits

Provides relief from allergy symptoms
Reduces sneezing and nasal irritation
Helps relieve itching and skin reactions
Long-lasting antihistamine action
Suitable for pediatric and adult use under medical supervision

Side Effects

Dry Mouth
Headache
Fatigue

Pharmcokinetic

Absorption: Rapidly absorbed after oral administration, peak plasma concentration reached in ~1 hour.
Distribution: Low protein binding (~93%), minimal penetration into the CNS due to limited blood–brain barrier crossing.
Metabolism: Minimally metabolized in the liver, majority remains unchanged.
Excretion: Primarily excreted unchanged via urine, renal clearance is the main route.
Half‑life: Approximately 8–10 hours in adults, shorter in children.

Contraindication

Hypersensitivity to Cetirizine or related antihistamines
Severe renal impairment (use with caution)

Dosage

As directed by the physician.

DRUG INTERACTIONS

Alcohol and CNS depressants: May increase drowsiness
Sedative medications: Additive sedative effects may occur

Warning and Precautions

This has been prescribed for the patient's specific condition. It may be dangerous to any other person.

Use cautiously in patients with liver disorders
May cause mild drowsiness in some individuals
Use during pregnancy or lactation only under medical advice
Avoid alcohol consumption during therapy
Store in a cool, dry place away from direct sunlight
Keep out of reach of children

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.